Soluble Dextrin Fibers Alter Intestinal Microbiota and Reduce Proinflammatory Cytokine Secretion in Male IL-10–Deficient Mice

American Society for Nutrition June 22, 2015

Structural differences in prebiotic fibers (soluble fiber) are associated with the stimulation of growth of distinctive gut microbiota in male IL-102/2 mice. Soluble fiber dextrin ingredients can induce the growth of butyrate- and acetate-producing microbes and reduce proinflammatory cytokine secretion in this mouse model of colitis. that were linked with specific immunoregulatory responses.

Vitamin D Deficiency Linked More Closely to Diabetes than Obesity

Endocrine Society February 23, 2015

Study finds direct correlation between low vitamin D levels, glucose metabolism

Washington, DC - People who have low levels of vitamin D are more likely to have diabetes, regardless of how much they weigh, according to a new study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism.



Interventions to lower the glycemic response to carbohydrate foods with a low-viscosity fiber (resistant maltodextrin): meta-analysis of randomized controlled trials

American Society for Nutrition / Am J Clin Nutr 2009;89:114–25.

A nonviscous palatable soluble polysaccharide can attenuate the glycemic response to carbohydrate foods. Evidence of an effect was stronger for RMD (resistant maltodextrin) in drinks than in foods.

Soluble fiber intake at a dose approved by the US Food and Drug Administration for a claim of health benefits: serum lipid risk factors for cardiovascular disease assessed in a randomized controlled crossover trial

American Society for Nutrition / Am J Clin Nutr 2002;75:834–9

The reduction in serum lipid risk factors for cardiovascular disease supports the FDA’s approval of a health claim for a dietary fiber intake of 4 servings/d. Although relatively small in terms of patient treatment, the reduction in cardiovascular disease risk is likely to be significant on a population basis.

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